When the King of Phoenicia plotted to murder his sister, Queen Dido of Tyre, over her claim to the throne, she gathered a force of loyalists and occupied the harbour at Tyre. Knowing she couldn't stand up to the full force of the Punic military, she embarked on a voyage to find a new homeland. She arrived on the shores of North Africa, and with a little diplomatic trickery, she managed to con the King of the Berbers out of a vast plot of land along the coast. She built a city on this land and named it Carthage. The name Carthage was derived from the Punic words meaning "new city."
Carthage quickly became a naval power that dominated the Mediterranean for centuries. They started forming colonies all over the coast of North Africa, and on some Mediterranean islands within their sphere of influence, including Corsica, Sardinia, Malta, and Sicily. Their most ambitious colonial adventure was the Iberian Peninsula, in modern-day Spain. They called their first Iberian colony Carthago Nova, or New Carthage. Reminder that Carthage itself translated to New City.
Centuries passed, and the Carthaginian Empire fell to the Romans. The people were displaced or enslaved, their capital was burned to the ground, and an amount of salt equivalent to the annual output of a League of Legends addict was rubbed into the Earth around Carthage. Other cities still stood however, Carthago Nova among them. The city eventually became known as Cartagena, and it was an important city in Spain for a while. When they started colonizing Central and South America, they, like many of the other European powers, began naming colonies after existing Old World cities. One of the Spanish colonies in modern-day Columbia was named New Cartagena. Again, reminder that Cartagena used to be Carthago Nova. Which was New Carthage. Which itself was New City.